Workshop program

Note that the exact titles and time slots of the presentations may be subject to change.

You can download a PDF version of the program here.

Thursday, 16 March 2023

8h30 - 8h45
Registration
8h45 - 9h15
Welcome address - Y. Prezado
SESSION 1: Radiobiology
Chair: R. Griffin
9h15 - 10h45
Invited presentations
  • Overview of what we know and don't know - R. Griffin (University of Arkansas for Medical Sciences, USA)
  • Review of radiobiological data from Institut Curie on proton and heavy ion MBRT - A. Bertho & L. Iturri (Institut Curie, France)
  • Review of radiobiological data from SNAKE - T. Schmid (Technical University of Munich, Germany)
  • Radiobiological models for particle minibeams - J. Seco (DKFZ Heidelberg, Germany)
  • Q&A
10h45 - 11h15
Coffee break
   11h15 - 12h30
Oral presentations from selected abstracts
  • Application of equivalent uniform dose (EUD) for the prediction of normal and tumor cell survival after proton minibeam irradiation - J. Stolz et al. (Technical University of Munich, Germany)
  • The effect of Minibeam and Microbeam Radiation Therapy on tumor growth delay in an in vivo mouse model - N. Subramanian et al. (Technical University of Munich, Germany)
  • Biological Models for a Preclinical Proton Minibeam Radiotherapy Facility - J. Neubauer et al. (Bundeswehr University Munich, Germany)
  • New insights into proton minibeam radiation therapy in healthy and tumoral cells using synchrotron-based Fourier transform infrared microspectroscopy - R. Gonzalez-Vegas et al. (Autonomous University of Barcelona, Spain)
  • Impact of spatially fractionated minibeams on the production of reactive oxygen species: a Monte Carlo study using TOPAS-nBio - T. Masilela et al. (Institut Curie, France)
12h30 - 13h30
Lunch break and poster session
SESSION 2: Technological aspects
Chair: J. Seco
13h30 - 14h15
Invited presentations
  • PMBT implementations at clinical centers - T. Schneider (Institut Curie, France)
  • PMBT implementations at research centers and new perspectives - G. Dollinger (Bundeswehr University Munich, Germany)
  • Q&A
14h15 - 15h00
Oral presentations from selected abstracts
  • Preclinical proton minibeam radiotherapy facility for small animal irradiation - A. Rousseti et al. (Bundeswehr University Munich, Germany)
  • Characterization of a novel preclinical proton minibeam set-up - M. Ahmed et al. (Helmholtz Center Munich, Germany)
  • LhARA end station dosimetry - An Evaluation of Preclinical Studies of Minibeam Radiotherapy for design of the LhARA end-station - J. McGarrigle et al. (Imperial College London, UK)
External vision and multidisciplinary discussion
15h00 - 16h00
External vision
  • Moderators: J. Seco & Y. Prezado
  • Invited experts: M. Durante (GSI, Germany), M.-C. Vozenin (CHUV, Switzerland), R. Griffin (University of Arkansas for Medical Sciences, USA), G. Arduini (CERN, Switzerland), A. Lombardi (CERN, Switzerland) & G. Datzmann (Datzmann interact and innovate, Germany)
16h00 - 16h30
Coffee break
16h30 - 17h30
Interactive multidisciplinary discussion
  • Knowledge gaps
  • How to move forward?
20h00 - 22h45
Gala dinner cruise
(arrival at boarding point 19h45 - 20h00)

Bateaux-Mouches
Pont de l'Alma
32 Port de la Conférence (Rive Droite)
75008 Paris

Friday, 17 March 2023

8h30 - 9h00
Arrival on site
SESSION 3: Physics and dosimetry
Chair: J. Eley
9h00 - 9h45
Invited presentations
  • Experimental dosimetry protocols for PMBT - I. Martínez-Rovira (Autonomous University of Barcelona, Spain)
  • PMBT dose calculation - L. de Marzi (Institut Curie, France)
  • Q&A
  9h45 - 10h45
Oral presentations from selected abstracts
  • CMOS Detector Robustness in pMBRT Dosimetry - S. Flynn et al. (National Physical Laboratory, University of Birmingham, UK)
  • Dosimetry and in vitro studies using a novel and versatile mini-beam collimator - C. Stengl et al. (DKFZ Heidelberg, Germany)
  • Biological optimization of peak-to-valley dose ratio for pMBRT - H. Gao et al. (University of Kansas Medical Center, USA)
  • Proton minibeam therapy is optimised by heterogeneous tumor doses and paves the way to proton FLASH therapy - J. Reindl et al. (Bundeswehr University Munich, Germany)
10h45 - 11h15
Coffee break
SESSION 4: Medical aspects
Chair: E. Jouglar
11h15 - 11h45
Invited presentations
  • Perspectives of spatially fractionated radiotherapy for clinical applications - S. Combs (Technical University of Munich, Germany)
  • Q&A
11h45 - 12h15
Oral presentations from selected abstracts
  • LIGHT proton linac minibeam FLASH plans, compared to photon SRS, and to FLASH and nominal LIGHT proton plans, for treatment of brain metastases - A. Kolano et al. (ADAM SA, Switzerland)
  • The dosimetric advantages of treating left partial breast indications with linac proton beams and minibeams versus cyclotron proton beams - K. O'Shea et al., presented by A. Kolano (ADAM SA, Switzerland)
12h15 - 12h30
Presentation of INanoTheRad - S. Lacombe (University Paris-Saclay, France)
12h30 - 13h30
Lunch break and poster session
Clinical perspectives and multidisciplinary discussion
13h30 - 14h30
Clinical perspectives
  • Moderators: E. Jouglar, R. Griffin, J. Eley & T. Schmid
  • Invited experts: Y. Kirova (Institut Curie, France), S. Tubin (MedAustron, Austria) & V. Hable (Bundeswehr University Munich, Germany)
14h30 - 15h30
Interactive multidisciplinary discussion
  • Knowledge and technology gaps
  • How to move towards clinical trials?
15h30 - 16h00
Coffee break
16h00 - 16h30
Workshop conclusion - J. Reindl